Who makes Kirkland Signature Mucus DM Maximum Strength (Guaifenesin 1200 mg / Dextromethorphan HBr 60 mg Extended-Release Tablets), 84 Tablets?
As of August 30, 2026, evidence points to Perrigo as the manufacturer of Kirkland Signature Mucus DM Maximum Strength (Guaifenesin 1200 mg / Dextromethorphan HBr 60 mg Extended-Release Tablets), 84 Tablets, but no tier 1–3 source names the link directly.
The common claim
What most answers say — and what the evidence supports
Store-brand roundups and Reddit threads generally credit Perrigo - the largest US maker of private-label OTC drugs - and note the tablets work like Mucinex DM. FDA drug records line up with that: Kirkland Signature Mucus DM (NDC 63981-812, guaifenesin 1200 mg / dextromethorphan HBr 60 mg) is marketed under ANDA 207602, whose Drugs@FDA applicant is Perrigo, and trade press documented Perrigo shipping the first store-brand equivalent to Mucinex DM's 1,200 mg extended-release tablets. The signal is indirect - the ANDA applicant is FDA's responsible party but not always the physical packer, and OTC lines like this are often multi-sourced - so the evidence points to Perrigo without rising to a flat confirmation.
Evidence & sources
Every source is graded on the six-tier rubric and archived, so the citation holds even if the original moves or paywalls. The tier badge grades the source; the status grades our confidence in the maker.
Tier 3
DailyMed's FDA-sourced label is titled "KIRKLAND SIGNATURE MUCUS DM (DEXTROMETHORPHAN HBR, GUAIFENESIN) TABLET, EXTENDED RELEASE [COSTCO WHOLESALE COMPANY]", names Costco Wholesale Company as the labeler (establishment DUNS 103391843), lists NDC 63981-812 (guaifenesin 1200 mg / dextromethorphan HBr 60 mg, 12-hour extended-release tablets), and in Marketing Information gives Marketing Category "Abbreviated New Drug Application" with Application Number ANDA207602. No establishment or registrant other than Costco appears on the SPL, so the deterministic link runs through the ANDA number rather than an on-label "manufactured by" line. This is the brand-to-ANDA anchor; the sibling source (openFDA Drugs@FDA) resolves ANDA207602 to Perrigo.
Tier 3
FDA's Drugs@FDA database resolves ANDA207602 - the application under which Costco markets Kirkland Signature Mucus DM (NDC 63981-812) - to sponsor/applicant PERRIGO R AND D (Perrigo). The original application was approved 2018-03-05 and covers guaifenesin / dextromethorphan HBr extended-release tablets in two strengths (1200 mg / 60 mg, the Kirkland Mucus DM strength, and 600 mg / 30 mg). Perrigo is the largest US maker of private-label OTC drugs. Graded probable, not confirmed: the ANDA applicant is FDA's responsible party for the product but is not always the physical packer, and OTC store-brand lines are frequently multi-sourced across NDCs and ANDAs.
Tier 4
Trade-press corroboration that Perrigo has been the store-brand maker of this exact formulation: "Perrigo Co. and Allergan plc have rolled out guaifenesin 1,200-mg and dextromethorphan HBr 60-mg extended-release tablets ... the product marks the first over-the-counter store-brand equivalent to Mucinex DM 1,200-mg ER tablets from Reckitt Benckiser (RB)." Context on why the sponsor landscape is narrow: Reckitt (which acquired Adams Respiratory Therapeutics, the Mucinex maker, in 2008) held the branded Mucinex NDA and its extended-release guaifenesin patents, so few generic makers cleared that hurdle. Dated 2016 and about a distribution partnership; the specific Kirkland Mucus DM NDC 63981-812 now sits under Perrigo's own ANDA207602 (approved 2018), which is the anchor of this record.
Frequently asked
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